Description

JWH-200 for Sale Online

JWH-200 for Sale Online. JWH-200 (1-Pentyl-3-(1-naphthoyl)indole) or AM-678 is an analgesic chemical from the naphthoyl indole family that acts as a full agonist of the cannabinoid receptors CB1 and CB2 with some selectivity for CB2 action. It causes effects in animals similar to that of tetrahydrocannabinol (THC), a cannabinoid naturally found in marijuana, leading to its use in synthetic marijuana products, sold legally as “incense blends” in some countries. Buy Research Chemicals JWH-200

JWH-200 metabolism was assessed using Wistar rats fed an ethanolic extract containing JWH-200. Urine was collected for 24 hours followed by extraction of the JWH-200 metabolites using liquid-liquid and solid phase extraction. GC-MS was used to separate and identify the extracted compounds. JWH-200 and its N-dealkylated metabolite were detected only at low levels, i.e. B. A hydroxylated N-dealkylation metabolite containing a primary signal. The observed mass shift indicates that hydroxylation is likely to occur in the naphthalene and indole moieties. Human metabolites are similar, although most of the metabolism occurs at the indole ring and the pentyl side chain, and the hydroxylated metabolite is highly conjugated to glucuronide.

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The media reported at least one case of JWH-200 addiction. Users consumed JWH-018 daily for eight months. Withdrawal symptoms are more severe than those resulting from marijuana addiction. JWH-200 has been shown to cause major changes in CB1 receptor density after administration. It causes a more rapid desensitization to its effects than the related cannabinoids.